Selank is one of the rising nootropics today. What is it exactly, and what are its potential benefits? Let’s find out.
Disclaimer: The purpose of this post is to present medical studies and information in an accessible manner. This post may contain opinions about this particular drug but it does not mean that it is recommended for all readers. Always consult a medical professional to see if these solutions may be right for you.
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In this article:
What Are the Benefits of Selank and Other FAQs
What Is Selank?
Selank, also known as TP-7, is a synthetic peptide derived by combining the sequence of tuftsin with another sequence to improve its stability. Tuftsin makes up one part of the IgG antibody and is naturally occurring.
Tuftsin Definition: A peptide closely related to the immune function primarily supported by the spleen
On top of its immunity boosting, anti-anxiety, antidepressant, and antiasthenic properties, it can also enhance memory and cognitive function. This peptide can potentially replace stimulants, tranquilizers, and antidepressants.
Antiasthenic Definition: A drug that counters asthenia, a disorder characterized by an abnormal physical weakness or lack of energy
While research isn’t yet conclusive, there are studies that observed the ability of Selank to stabilize blood enkephalins—natural peptides in the body that can reduce stress. Another research also reported it to have been able to change levels of serotonin, dopamine, and norepinephrine, the neurotransmitters involved in motivation, focus, and pleasure.
What Are the Potential Benefits of Selank?
Given the current data on Selank, here are the potential benefits you can get from taking it.
1. May Improve Anxiety
Selank is an anxiolytic peptide, which helps combat stress and anxiety. Here’s what the literature says about this:
- A study with a randomized controlled trial of 62 patients found out that those who took Selank had fewer symptoms of anxiety. One promising caveat observed in the same study is the greater decrease in those participants with pre-existing anxiety disorders.
- This similar effect was observed in another randomized controlled trial with 60 anxiety and phobia patients.
- A study of 70 anxiety patients reported that Selank increased the effects of phenazepam, a banned anti-anxiety drug in the U.S. while reducing its side effects.
- Studies in mice also showed Selank’s anxiolytic effects. The more anxious a subject is in the beginning, the more significant the result is.
- Another animal study confirmed the long-term anxiolytic effect of Selank without causing any changes in body mass.
While these findings show promising Selank benefits, it is important to remember to seek your doctor’s approval before using Selank in treating anxiety disorders. As a general rule, you should never take any peptide or medication other than what your physician prescribed.
2. May Improve Learning Ability
A study in mice showed Selank’s capability to improve learning ability within three days. The subjects treated with the peptide learned quicker on an electrical test.
Other effects observed were reduced anxiety, helping them move faster.
3. May Enhance Memory
In a 30-day trial in rats, Selank showed to have stabilized memory traces in rats. It is unclear, however, how the measurements were done since memory traces aren’t detectable as locations in the brain.
There’s also a study that concluded it might preserve memories in monkeys.
4. May Help with Brain Damage Recovery
Researchers found Selank to restore the brain activity of mice with toxin-induced brain damage to normal levels.
5. May Increase Liver Antioxidant Activity
A study in mice showed that injecting the stressed subjects with Selank increase the levels of antioxidants in their livers.
6. May Help Strengthen Immune Function
In one study, Selank increased blood IL-6, an inflammatory protein that can help fight infection, levels of depression patients.
A different cell-based study found that Selank induced the release of the anti-viral molecules interferons. In this study, it did not show any treatment effect in virus-infected mice.
7. May Help with Alcohol Withdrawal
In one study, rats were given a 10% ethanol solution as their only drinking source in the span of 24 weeks to recreate alcohol intake. It found out that Selank decreased alcohol-withdrawal-related anxiety of the rats after a 48-hour period.
8. May Help with Blood Pressure Management and Increase Brain Blood Flow
Selank decreased the blood pressure of sedated cat subjects by about 30% for 3 minutes in this study. It also increased the cats’ brain blood flow by about 24% for up to 10 minutes.
9. May Help with Weight Loss and Reducing Cholesterol
Researchers found that when treated with Selank, high-fat-fed mice gained 35% less weight. On top of that, the total cholesterol of the subject dropped by over 58%, while their blood sugar level decreased by 23.5%.
10. May Improve Ulcers
Selank decreased the area of stomach ulcers in animal research subjects. This is attributed to the peptide’s ability to increase lymph flow to the stomach.
11. Helps Reduce Stress
Stress can be caused by a lot of different things, and the body reacts to it in various ways, as well. For instance, some bodies respond to stress by increasing the production of liver enzymes.
One study conducted on rats showed that Selank reduced liver enzyme production.
Additionally, a separate experiment found that Selank may influence the effect of benzodiazepine drugs. The study concluded that when combined with diazepam, it can provide a favorable effect in reducing anxiety in chronic mild stress conditions.
Benzodiazepine Definition: A type of tranquilizer
12. May Help with Parkinson’s Disease
Parkinson’s disease is a neurodegenerative disorder characterized by muscular rigidity, slow and imprecise movement, and tremors. Clinical trials found significant results, such as:
- Improved mood
- Decreased tremors
- Better sleep quality
- Decreased tearfulness
- Lively reflexes
How Do You Use Selank?
Selank is a peptide taken nasally. This is because the stomach digests it if taken orally.
Inhaling it is a better way to deliver it to the brain. The recommended dosage is 2-3 tiny drops in each nostril for 2-3 times a day.
To lengthen the lifespan of this peptide to 24 months, its shelf temperature should be at 35.6 – 46.4°F. Take note that when Selank is stored at room temperature, it only lasts over 90 days.
While injections are a good alternative to nasal dosage, make sure to get them from a doctor. It is also important to note that it is considered less effective than nasal sprays or drops.
Dosages vary depending on your health condition. To get the right Selank dosage, a medical examination must be done.
Generally, the dosage for Selank injection must range between 250 mcg – 3 mg per day.
Its administration can be done intramuscularly (into the muscle) or subcutaneously (under the skin). Usually, Selank is injected into the stomach fat area, shoulder, buttocks, and thigh.
What Are the Kinds of Selank Available?
You can buy Selank in three forms:
- Selank – This form is commonly researched on.
- NA-Selank – AKA N-acetyl Selank, this is closely similar to Selank minus the acetyl group in its bond. No human studies have been done on this form.
- NA-Selank Amidate – There are no existing studies that mix Selank with Amidate, a prescription anesthetic.
How Is It Different from Semax?
Both are synthetic peptides that have potential nootropic benefits. Semax, however, comes from a brain hormone and has different uses—preventing liver damage and improving blood circulation.
Selank and Semax are both nootropics that were developed in Russia. In some cases, they can be used for similar purposes.
Selank is an anxiolytic peptide that minimizes the harsh effects of stress and it’s known to have fewer side effects when compared to Semax.
Selank and Semax are both potentially amazing cognitive enhancers. Semax is more potent in enhancing cognition and depression. Selank, on the other hand, shows better results when used for anti-anxiety purposes.
What Other Things Should I Consider Before Taking It?
Although the data available for now, both from animal and human studies, are promising, there is no guarantee of this peptide’s therapeutic effects.
- Although it contains a stabilizing protein sequence, Selank’s half-life is only two minutes—after 10 minutes, it becomes completely untraceable in the bloodstream. This opens the question of whether the peptide can really have long-lasting effects.
- At the moment, we have limited information about its activity on human patients.
- There are currently no reported side effects. Extensive research is still needed to prove if this peptide is safe.
With the early findings on Selank’s possible benefits, it might be encouraging for many people to take it. But there’s still much left to be learned about it. Even though it can stabilize protein sequence, the half-life of Selank is only 2 minutes. It cannot be detected in the body 10 minutes after being taken.
The information available on Selank’s effects on the human body is very limited because there are only three published clinical studies about Selank.
The potential side effects of Selank are also unknown due to the lack of data. It cannot be taken orally because the stomach cannot digest it. Selank can only be taken by injections or nasal administration which could cause various side effects but such possible side effects have not been studied yet.
For other supplements supporting protein sequences in the body, check out Dr. Seeds’ shop.
Where Can You Buy Selank?
This drug is available only in Russia. It isn’t readily available in the U.S. because the FDA regulates synthetic peptides in the U.S.
Selank poses a great potential as a nootropic and an anxiolytic drug. With the lack of definitive scientific verdict on its effectiveness and safety, it is the best course of action to consult your doctor first before trying it.
Also, keep in mind that there are natural ways to promote health and wellness. You should remember to eat a well-balanced diet rich in fruits, vegetables, and whole grains.
It’s also helpful to keep a regular physical activity, such as walking, jogging, running, or swimming. Make sure you get enough hours of sleep as well as it helps a lot in keeping your body energized and in top shape.
Also, stay away from stress because it plays a part in several health problems ranging from simple headaches to depression and anxiety. You can manage your stress by trying relaxation techniques like yoga and meditation.
For other supplements supporting protein sequences in the body, check out Dr. Seeds’ shop.
Do you have any other questions about Selank? Let us know in the comments section below!
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Editor’s Note: This post was originally published on June 19, 2019, and has been updated for quality and relevancy.