Estrogen Hormone Therapy: Pill, Cream, Patches and More

woman holding cream and wearing bathrobe | feature | Estrogen Hormone Therapy: Pill, Cream, Patches and More
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In various forms, estrogen hormone therapy can provide women with different benefits, from pills to creams. Find out more about different types of estrogen hormone therapy.

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In This Article:

  1. Viginal Rings, Vaginal Creams, and Suppositories
  2. Estrogen Creams, Sprays, and Gels 
  3. Estrogen Patches
  4. Estrogen Pills


The Effects of Estrogen Cream and Other Treatments

Vaginal Rings, Viginal Creams, and Suppositories

woman holding Vaginal Rings | Estrogen Hormone Therapy: Pill, Cream, Patches and More

These types of hormone therapies are used directly on the vaginal region. In general, these medications are intended for women who experience vaginal dryness, itchiness, burning, or discomfort during intercourse.

Each treatment will have different applications and individual dosing schedules. For instance, vaginal rings must be patched after three months. Vaginal tablets are often used regularly for a few weeks before being reduced to twice a week. Creams should be used every day, for several days a week, or on a separate timetable.

  • Pros: Some vaginal suppositories and rings are low-dose, affecting just the surrounding region. They have the benefit of alleviating vaginal complications without exposing the whole body to heavy levels of estrogen. In addition, you don’t need to worry about taking estrogen supplements every day, like when using estrogen pills and tablets.
  • Cons: As rings and suppositories only have a small dose of estrogen, they can only help with the vaginal symptoms of surgical menopause. Therefore, they can’t help you with symptoms like hot flashes.


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Estrogen Creams, Sprays, and Gels

Estrogen creams, sprays, and gels offer another method for providing you with estrogen. This routine of estrogen therapy is absorbed directly into the bloodstream through the skin. The nuances of how to use these creams differ, but they are usually used once a day.

  • Pros: Since estrogen creams are absorbed by the skin and straight into the bloodstream, they are less dangerous than oral estrogen for people with liver and cholesterol issues.
  • Cons: Estrogen gels, creams, and sprays have not been thoroughly researched. Experts are divided on whether they are better than oral estrogen. Assume they face the same minor risk of medical conditions such as cancer and stroke.


Estrogen Patches

woman applying estrogen patches | Estrogen Hormone Therapy: Pill, Cream, Patches and More

This type of estrogen hormone therapy allows you to increase estrogen level by applying it onto the lower stomach area below the waistline.

  • Pros: While estrogen tablets may be unsafe for people with liver disorders, estrogen patches are safer since the estrogen bypasses the liver and enters the bloodstream directly. In addition, with the easy-to-use patch, you can stick it on and don’t need to worry about taking a pill every day. A 2007 study has found that the patch does not increase the risk of blood clots in postmenopausal women as oral estrogen does, but further research is required to determine if patches are better than tablets.
  • Cons: Though scientists believe that this type of estrogen treatment is safer, it’s too early to come to that conclusion. Therefore, just like other hormone replacement therapy, it still has some risks such as swollen breasts, nausea, headache, vaginal discharge, cancer, and stroke.


Estrogen Pills

woman having a cup of tea | Estrogen Hormone Therapy: Pill, Cream, Patches and More

Unlike estrogen cream and other therapy, this is the most conventional and most well-known estrogen treatment. These oral medications are conjugated estrogen, and most of them are taken once a day without, and some have a more complex schedule.

  • Pro: Estrogen tablets, like other estrogen therapy forms, can help alleviate or eliminate menopausal symptoms. They will also help to reduce the risk of osteoporosis. Though there are newer methods of obtaining ERT, oral estrogen medications are the most thoroughly researched form of estrogen therapy.
  • Cons: The risks with this form of hormone therapy have received a lot of attention. Strokes, blood clots, and other complications are all increased from estrogen alone. When paired with the hormone progestin, the chances of breast cancer and heart disease can increase. They can also have side effects such as nausea, vaginal discharge, headache, and swollen breast.


These hormone replacements, from topicals to congested estrogen pills, are all successful in assisting you in stabilizing the estrogen levels in your body. However, the dose, schedule, and type of estrogen treatment vary depending on the person’s health status and hormone level. Therefore, consulting with your healthcare providers is a must before you start using any of these hormone replacement therapies.


Have you tried estrogen cream or any other kind of estrogen hormone replacement therapy before? Let us know your experience in the comment section below! 


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