How can Body Protective Complex-157 or BPC-157 help your body heal faster? Learn more about this peptide below.
Disclaimer: The purpose of this post is to present medical studies and information in an accessible manner. This post may contain opinions about this particular peptide but does not mean that it is recommended for all readers. Always consult a medical professional to see if these solutions may be right for you.
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In this article:
- What Is BPC-157?
- What Is a Peptide and How Do Combinations of Amino Acids like BPC-157 Potentially Support Health?
- What Are the Peptide Sequences in BPC-157?
- Can BPC-157 Benefit Joint and Tendon Healing?
- Can BPC-157 Help Reduce Joint Pain and Increase Flexibility?
- How Can the Peptide Help the Gut?
- What Other Benefits Can BPC-157 Have?
- How Is BPC-157 Taken and What Are Common Doses?
The Importance of Body Protective Complex to Your Health
What Is BPC-157?
BPC-157 or Body Protective Complex is a peptide or a combination of amino acids. It can be found in human stomach juices (gastric juices).
It may have the potential to speed up healing. The BPC peptide can also promote joint and tendon health and help blood vessels to regenerate (angiogenesis).
Some people who have used BPC-157 refer to it as the “Wolverine” supplement. Research primarily tested Body Protective Complex-157 on animals.
In animal testing, it showed benefits in healing after muscle injuries, tendon strains, and burns. It also manifested the ability to help animal blood vessels grow and regenerate.
Even better, BPC-157 can reduce the risks of oxidative stress, which is the imbalance of free radicals and antioxidants in the body.
High levels of oxidative stress can result in chronic inflammation. It may affect vital organs such as the heart and the blood vessels.
It will then boost the risks of developing conditions such as high blood pressure (hypertension) and heart disorders. Using BPC-157 can potentially benefit many aspects of healing and the health of the cardiovascular system.
Body Protective Complex can also modulate nitric oxide, which works as a vasodilator. In the process, this peptide can regulate low and high blood pressure.
What is a vasodilator? It is a substance that can widen or dilate the blood vessels.
What Is a Peptide and How Do Combinations of Amino Acids like BPC-157 Potentially Support Health?
Peptides are compounds of amino acids that occur naturally in the body or which can be synthesized. BPC-157 is a combination of 15 amino acids, also called a pentadecapeptide.
Researchers at Emory University discovered these simple peptides could organize into tissue membranes. Their research published in 2010 in the journal of the German Chemical Society, Angewandte Chemie, showed how peptides built up crucial elements of membranes.
The Emory scientists observed the peptides assembling into layers, functioning similarly to more complex proteins.
What Are the Peptide Sequences in BPC-157?
BPC has the following molecular formula:
Combined, the molecular formula results in the following sequence of 15 amino acids:
L-Valine, glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-; glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolylglycyllysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-L-valine
In the human body, this sequence protects and heals the gut or the gastrointestinal tract.
Individually, some of these amino acids may have familiar names. They are also recognized as being potentially useful in muscle recovery and healing process.
How Can BPC-157 Benefit Joint and Tendon Healing?
Researchers conducted several studies on rodents using Body Protective Complex-157. It is to test whether the supplement can help to heal tendons and joints.
A 2011 study published in the Journal of Applied Physiology described how BPC-157 sped up the healing of rat Achilles tendon.
When the rats were put under stress, BPC-157 continued to speed up healing. The rats under stress without BPC-157 experienced slower healing.
A 2014 study published in Molecules explored whether growth hormone receptors increased in rat tendon cells (called fibroblasts) with the use of BPC-157. The study showed the cells did have more growth hormone receptors when BPC-157 was used.
In similar research, scientists discovered Body Protective Complex can quicken the healing of rats with Achilles tendon transection. It could be because it stimulates the growth of tendocytes or tendon cells.
What is transection? It is the process of cutting something transversely (crosswise direction).
BPC-157 can become another possible therapy for injuries involving a transection. Some of these may affect the quadriceps muscle and medial collateral ligament tissue.
Scientists are studying ways to regenerate and heal ligaments and tendons since the early 2000s. Researchers tested different types of protein.
As a peptide, a smaller and simpler collection of amino acids than a protein, it may support healing in a different way than protein.
Body Protective Complex, therefore, is helpful for people with issues involving their connective tissue.
Can BPC-157 Help Reduce Joint Pain and Increase Flexibility?
Some bodybuilders used Body Protective Complex-157 to speed up the recovery time. They also used it to reduce pain after working out.
Rodent studies on the peptide focused on the supplement’s ability to heal tendon cells. They showed it improved blood flow.
The peptide can also stimulate cell survival and cell migration. Other rodent studies showed it promotes improved bone-to-tendon healing.
The peptide also showed to reverse medication-impaired muscle healing. These qualities may contribute to increased flexibility and reduced joint pain.
Body Complex Peptide reviews by some bodybuilders refer to using BPC-157 to help heal a torn upper hamstring.
RELATED: Tips For Healthy Joints At Every Age
How Can the Peptide Help the Gut?
BPC-157 in human gastric juices helps to protect and heal the gut. Rodent studies have shown it has helped to reverse stomach and gut damage caused by taking NSAIDs like Advil or ibuprofen.
Some people have used the peptide to help repair damage affecting the intestines:
- Inflammatory bowel disease (IBD)
- Short bowel syndrome
In one of the studies, the peptide BPC-157 could be helpful for people who suffer from Crohn’s disease. It is a condition characterized by the chronic inflammation of the intestines, especially the colon.
A person with Crohn’s disease will develop lesions, ulcerations, or other perforations of the small intestines. These can then lead to symptoms such as fatigue, weight loss, and malnutrition.
Depending on the severity of the malnutrition, it may increase the risks of other chronic diseases. The wounds can also boost the chances of colorectal cancers.
Because Body Protective Complex is stable in the stomach, those with Crohn’s may be able to tolerate higher doses. It may also promote the formation of granular tissue or granulated vascular tissue
It then makes BPC-157 a potential peptide therapy for wound healing affecting the gut or the colon.
Body Protective Complex also showed benefits in healing the brain-gut axis, which is actually a nerve. This explains why it may be an ideal therapy for individuals with conditions such as Parkinson’s disease.
Other Body Protective Complex reviews refer to benefits in improved mood and impulse control. Some animal studies showed the peptide may have benefits in increased dopamine and other helpful brain chemicals.
What Other Benefits Can BPC-157 Have?
The peptide also helped to improve periodontitis (gum or periodontal disease) in rats, as well as bone defects.
When tested in rabbits with bone defects, BPC-157 helped to accelerate bone healing. Based on the results, it could mean Body Protective Complex will be significant for individuals with gastrectomy.
Gastrectomy is a surgery involving the removal of a part of the entire stomach. One of the possible reasons is stomach cancer.
Patients who underwent such procedure tend to have a higher risk of injury affecting the bones such as a fracture. They may also develop osteoporosis, in which the bones become fragile and brittle.
The research showed one of the healing properties of BPC-157 is osteogenic. It can support the formation and healing of bones, working as a growth factor.
It may even be more potent when combined with other forms of treatment. These include the autologous implantation of the cortical bone or bone marrow.
How Is BPC-157 Taken and What Are Common Doses?
Medical professionals usually injected the peptide directly into muscles or subcutaneously (subcutaneous injection) into fat. Most research studies in rodents were conducted with BPC-157 injections.
On the other hand, the remainder of the studies used BPC-157 orally administered supplements.
Body Protective Complex supplements are also available in pill form. Studies have also shown the peptide can last for up to 24 hours in stomach acid.
When it comes to BPC-157 dosing, BPC-157 doses are measured in micrograms (μg/mcg).
A 154 lb/70kg person’s recommended oral dose is 112μg/mcg. A 198lb/90kg person would have a recommended dose of 144μg/mcg.
Don’t forget to download, save, or share this handy infographic for reference:
Body Protective Complex, or the Wolverine” peptide, is a combination of amino acids that have the potential for healing. It can also support muscle recovery.
BPC-157 may also help rebuild and renew muscles after bodybuilding, as well as after incurring sports injuries.
It can also potentially improve healing after surgery. To maximize its benefits, it is better taken in the form of oral supplements with proper medical guidance.
Check out this video to understand more about BPC-157 and its benefits:
What do you think about Body Protective Complex? Share your thoughts in the comments section.
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Editor’s Note: Dr. Seeds’ Body Protective Complex is a natural daily oral supplement that uses the larger protein from which BPC-157 is extracted. While there are no known side effects, it is best to consult a doctor before intake, especially if you are lactating, pregnant, taking prescription drugs, and with a pre-existing condition.
Editor’s Note: This article was originally published on December 13, 2018, and has been updated for quality and relevancy.